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In the final hunt of the year, the hunters descend on Florida's Lake Elizabeth Wetlands and go to battle with pythons gaining a foothold in this vital ecosystem, pushing their limits to safeguard paradise.

Swamp People: Serpent Invasion

Do or Die

The hunters push past the point of exhaustion in the final stretch of python season, tempting fate in panther country, gambling on isolated hotspots, and searching into the dead of night.

Unfamiliar Territory

Pickle learns to drive an airboat on the fly; Zak and Aaron go after two invasive species at once; Bruce and Kaylyn fight through skin-shredding sawgrass; Dusty tests recipes for a new Everglades culinary sensation.

Razor's Edge

As the excessive heat begins to wear on the hunters, the King of the Swamp launches a contest to catch the biggest python; each hunting team uses their local knowledge to devise different strategies, hoping to come home the winner.

Python Showdown

Troy and Pickle struggle to take command of a friend's hunting dog; Zak and Aaron deploy kayaks deep into an untested area; Bruce and Kaylyn explore an isolated island with a gruesome past.

On the Scent

The teams unite to storm a hostile site that's rumored to be swarming with pythons; attacking by land, water and air, the teams deploy buggies, boats and drones to target and eliminate a growing threat to the Everglades.

Badwater

Troy and Pickle call in a chopper to reach a remote hunting spot deep in the Everglades; Zak and Aaron attempt a bold new strategy using fish chum to attract snakes; Bruce, Kaylyn and Dusty experiment with radical new ways of trapping pythons.

Desperate Measures

Zak and Aaron team up with a gladesman promising to bring them to a python jackpot; Troy gets his old partner Pickle back into fighting shape; and Bruce and Kaylyn return to a monster's den.

Jackpot

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Legendary hunters try to capture Burmese pythons that are decimating the Florida Everglades and wiping out entire species.

S5 E1 | Jackpot