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Lupe has spent the last 10 years in bed and is totally dependent on her husband, prompting a cross-country move that could save her life or end up backfiring.

My 600-Lb. Life

Lupe's Story

Sean has a massive growth protruding from his side and skin so stretched it's tearing apart, forcing his mother to change both of their lifestyles before he can be approved for surgery.

Sean's Story

Milla is bedridden and dependent on her husband and five kids, who can't resist her unending requests for junk food.

Milla's Story

Randy's food addiction dissolved his marriage and keeps him from seeing his daughter, so he endures a rigorous pre-surgery diet surrounded by fast-food temptations to regain control of his life.

Randy's Story

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

Teretha's Story

Ashley confronts medical setbacks and struggles to get past the trauma that ignited her eating disorder.

Ashley D.'s Story

At 650 pounds, Gideon's weight prohibits him from working, making him completely dependent on his exhausted wife.

Gideon's Story

Dottie wants to be a better mom, so she agrees to a drastic new diet, but her child's life-threatening emergency and her own self-sabotage threaten to derail all hopes for weight-loss.

Dottie's Story

June copes with the tragic death of her son by eating, and must confront the emotional issues driving her food compulsion after gastric bypass surgery.

June's Story

After gastric bypass surgery, Chad quickly sheds his dangerous weight but faces a medical crisis when he does not follow the doctor's orders.

Chad's Story

Brittani married a man who loves large women, but at 600-lbs, she can barely contribute to their marriage, and gets surgery to try to have a normal relationship.

Brittani's Story

Nikki finds her career as a costume designer threatened by immobility, so she undergoes gastric bypass and confronts the emotional causes for her eating.

Nikki's Story

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The medical journeys of morbidly obese people are told, as the people attempt to confront lifelong emotional and physical struggles and make the courageous decision to undergo high-risk weight-loss surgery.

S4 E12 | Sean's Story