Return to Me (2000)

Heartbroken and struggling emotionally after his wife's death in a car accident, Bob Rueland (David Duchovny) agrees to go on a blind date set up by his friend Charlie (David Alan Grier). Though the date fizzles, sparks fly between Bob and the waitress, Grace (Minnie Driver), a recovered heart transplant patient with intimacy problems of her own. When Bob discovers Grace's heart came from his own organ donor wife, an unusual romance blossoms between the two.